Canine DNA Profiling and Parentage Analysis
DNA Profiling, also known as "DNA Fingerprinting" or "Genotyping" establishes a genetic code for individual dogs of every breed. This test does not determine breed type, rather, it identifies specific gene markers that are inherited from both parents.
Animal Genetics currently offers the ISAG (International Society for Animal Genetics) standard panel, which consists of 18 STR markers. This panel identifies highly polymorphic markers to determine the most informative genetic code for any dog. The DNA profile of a dog consists of two alleles for each marker, one that was inherited from the mother, and one that was inherited from the father.
Canine DNA profiling is a useful tool to accurately identify your dog, particularly in case a dog is stolen, or to prove parentage.
Important!: DNA Profiling DOES NOT determine the breed of a dog.
DNA Profiling is an efficient and extremely accurate way of proving parentage as well. In cases where the sire of a litter is uncertain, the DNA profiles of the mother, father, and offspring can be compared. Any alleles that are present in the offspring that did not come from either parent can exclude the parent/offspring relationship.
Example of report: "Canine Parentage Report"
"Clear by Parentage"
If a parent/offspring relationship is established, and both parents test negative for a genetic disease at our lab, the report for the offspring will indicate that the offspring is "clear" for a mutation. All "Clear by Parentage" results require a Parentage Verification, to be performed at our lab. This is done to ensure the accuracy of the results, and to prevent against any possible fraud or irresponsible breeding practices.
Animal Genetics will verify parentage for any parent/offspring, however, we will not indicated that a dog is "cleared by parentage" on the certificate of the offspring. A report will still be issued displaying the relationship between the parents and the offspring.
Standard Canine Marker panel:
Animal Genetics follows the standards set by the International Society of Animal Genetics (ISAG) and leading labs including The University of California Davis (U.C. Davis). All our profiles use a multi-plex genetic STR marker panel, consisting of 18 Loci: AHT121, AHT137, AHTh171, AHTh260, AHTk211, AHTk253, C22-279, FH20545, FH2848, INRA21, INU005, INU030, INU055, REN162C04, REN169D01, REN169O18, REN247M23, CAN-AMEL creating reliable results that are accepted throughout the world.
Animal Genetics accepts Buccal Swab, Blood, Dewclaw. Collection kits are available and can be ordered.
Results are given using symbolic as well as numeric notation. All results are available by email.